Optimizing bead size reduces errors in force measurements in optical traps

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Optimizing bead size reduces errors in force measurements in optical traps.

Optical traps are used to measure force (F) over a wide range (0.01 to 1,000 pN). Variations in bead radius (r) hinder force precision since trap stiffness (k(trap)) varies as r3 when r is small. Prior work has shown k(trap) is maximized when r is approximately equal to the beam waist (w0), which on our instrument was ~400 nm when trapping with a 1064-nm laser. In this work, we show that by cho...

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ژورنال

عنوان ژورنال: Optics Express

سال: 2013

ISSN: 1094-4087

DOI: 10.1364/oe.21.000039